The African Continental Free Trade Area (AfCFTA) creates one of the largest single markets in the world, measured by the number of countries participating and the people involved. The pact connects 1.3 billion people across 55 countries with a combined gross domestic product (GDP) valued at USD 3.4 trillion (World Bank, 2020). Projections by the World Bank show that by 2035, the volume of total exports would increase by almost 29%, intra-regional continental exports would increase by more than 81%, and exports to non-African countries would rise by 19% (World Bank, 2020). The AfCFTA Agreement allows Tanzania to face the current trade and economic development challenges in a manner that will significantly assist in growing the country’s trade volumes and economy. Tanzania has a comparative and competitive advantage in agricultural production and intra- regional trade. Factors such as its strategic location enable easy access to ports, infrastructure, and border points that are strategic regional trade and investment channels. Tanzania’s different agro-ecological zones can produce a variety of food commodities, while it’s stable economy and political environment are conducive to foreign investment. If utilized effectively, the country will significantly benefit from this trade Agreement. Additionally, The AfCTA has the potential to enable Tanzania’s small and medium enterprises that dominate the economy to integrate into the regional and global value chains and trading systems.